There are several approaches to consider when building your virtual offering. Above all else, keep it simple. Remember most of your audience are watching on their computer. Consider this your starting parameter.
Define your format: is this a one-on-one meeting, a seminar, a conference, a performance.
If you are seeking a more personalized, one one one experience, a straightforward screen to screen setup will be fine.
If you are a lecturer or performer, consider building your virtual performance around the concept of a standup comedy special or seminar. If you are a musician or ensemble consider how your live performance translates to the virtual space. Would your performance benefit from multiple camera angles, or is a single camera aesthetic engaging to your audience.
If your offering is more involved with a longer performance, or multiple performers consider a conversational format with multiple people talking to each other. A variety of speakers makes for more engaging discussion. Or approach things as if you are a TV producer, incorporating programming blocks (individual segments for each element of your program), interstitials between acts, etc. Perhaps you will have a host or MC to engage your virtual audience between each segment.
If you have a multi-part, multi-day event think about how you will tie the larger program together. Would you like your program to have a uniform look in terms of title cards, animation, etc. Will you incorporate teasers or ads into the program, or information on ‘what’s next.’
Ultimately, what is the core of what you do? Make a list of what is the essence of what you do and why people come see you. The question is not if this can be adapted but how can this be adapted to a virtual setting? Almost every presentation can be adapted.
And finally, whatever the current duration of your offering is, shorten it! Attention spans are shorter online.